I did this shoot sometime back.. First let me present the outcome and then describe what it is.

Most would not be able to guess what this is apart from the fact these are water droplets....Oh! Believe I gave it away with the title of this post. During the winter, I was exploring indoors for a shot and saw a snow globe and the water droplets formed on top of it. Here s how it looked like.

Pretty boring ha? Not for me! :). So, there we go... carefully moved it a desk...Used two colored LED lights (From a dollar shop) and pointed the lights from either side of the globe from below. Didn't have a descent tripod..so took this handheld at f/5.6. Also used extension tubes to get close up (No macro lens :D).... and snapped away...!

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Akila.